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09 Set

Farías J, Feleder E, González E, Halabe K, Criscuolo ME, Bergadá I, Diez RA.
  • 09/09/2010

Relative bioavailability of two drug products of somatropon obtained from the milk of transgenic cows or bacterial culture. Horm Res Paediatr. 2010;73(4):258-64.

BACKGROUND:

Our objective was to assess the relative bioavailability of the first somatropin produced in transgenic cloned cows that carry the human growth hormone (GH) gene (Biohormon) and somatropin produced in Escherichia coli culture (HHT), the procedure most frequently used for the commercial production of the hormone.


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